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Implementing an IV Iron Maintenance Regimen Protocol in a Hemodialysis Practice
Cheryl Gilmartin, Kwanta Na-Thalang, Jose Arruda, and Alan Lau
Iron-deficiency
anemia is commonly encountered in patients with end-stage renal disease
(ESRD) requiring chronic hemodialysis and can occur as a result of
blood loss from frequent laboratory tests, blood retention in the
dialysis tubing and dialyzer, gastrointestinal (GI) bleeding, repeated
access surgery, poor oral iron intake and/or absorption, and low
protein diets (Sakiewicz, 1998; Eschbach, 1999). Further compounding
the deficiency is the use of recombinant human erythropoietin (EPO),
which stimulates erythropoiesis to abnormally high levels and leads to
functional iron deficiency in up to 90% of patients (Macdougall, 1995;
Sunder-Plassmann, 1997).
Cheryl Gilmartin, PharmD, is Clinical Assistant Professor, University of Illinois at Chicago, Chicago, IL
Kwanta Na-Thalang, MS, is Nephrology Research Fellow, University of Illinois at Chicago, Chicago, IL
Jose Arruda, MD, FACP, is Professor of Medicine; Chief, Section of Nephrology, University of Illinois at Chicago, Chicago, IL.
Alan Lau, PharmD, is Professor, University of Illinois at Chicago, Chicago, IL.
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