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Nephrogenic Fibrosing Dermopathy/Nephrogenic Systemic Fibrosis - Download article and take CE posttest
Karen Hamilton-Persaud
Loretta D. Ezell
Joyce G. Macklin

Nephrogenic fibrosing dermopathy  is a relatively new skin disorder affecting only individuals with renal failure. This disease resembles scleromyxedema with thickening and hardening of the skin of the extremities, but it is distinctly different. Nephrogenic fibrosing dermopathy has no consistently effective treatment and its cause is unknown; however, there are several documented theories as to the factors that may contribute to its development.  We present a brief overview of the literature and four patients with the disorder who share similarities in disease onset.


Karen Hamilton-Persaud, BSN, RN, is Nurse Manager, Dialysis Program, Duke University Health System, Durham, NC. She is a member of ANNA’s Cardinal Chapter. For more information on this article, contact the author at hamil045@mc.duke.edu.
Loretta D. Ezell, BSN, RN, CNN, is Clinical Operations Director, Dialysis Program, Duke University Health System, Durham, NC. She was the 2006-2007 President of ANNA’s Cardinal Chapter.
Joyce G. Macklin, RN, CNN, is Charge Nurse, Duke University Health System, Durham, NC. She is a member of ANNA’s Cardinal Chapter.