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A Clinical Review of Antibody-Mediated Pure Red Cell Aplasia - Download article and take CE posttest
Susan Vogel and Jérôme Rossert
Pure
red cell aplasia (PRCA) is a rare hematologic disorder characterized by
severe anemia from selective failure of the bone marrow to produce
mature red blood cells. This disorder can be congenital or acquired
from various causes. The development of PRCA in patients with chronic
kidney disease receiving recombinant erythropoietin (rHuEPO) for renal
anemia has increased in recent years. This review will enable nurses to
recognize the pathogenesis, clinical manifestations, and therapeutic
options for rHuEPO-induced PRCA.
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| Susan Vogel, MHA, RN, CNN,
the CEO and President of Renal Replacement Therapies, Encino, CA.
She is also an Administrator at South Valley Regional Dialysis Center,
Inc., Encino, CA; and a member of the Los Angeles chapter of ANNA.
Jérôme Rossert, MD, PhD, is
a Professor of Nephrology at the University Pierre and Marie Curie in
Paris, France. He is also a Consulting Physician in the Department of
Nephrology at Tenon Hospital, Paris, France; and a Senior Scientist at
the National Institute for Health and Medical Research (INSERM), Paris,
France.
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