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Extended Dosing of Darbepoetin Alfa in Patients With Chronic Kidney Disease Not on Dialysis:
A Review of Recent Data
Theresa Moore
Sarah Chookie
Anemia
is a common and serious complication of chronic kidney disease (CKD),
which can be successfully and safely treated with
erythropoiesis-stimulating proteins (ESPs). Darbepoetin alfa, a
long-acting ESP, can be dosed less frequently than Epoetin alfa,
thereby reducing the burden on patients and health care staff. This
review summarizes recent clinical data supporting use of darbepoetin
alfa at extended dosing intervals of once every 2 weeks and once
monthly in patients with CKD not on dialysis.
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| Theresa Moore, MSN, RN, NP, APRN, BC, is
Nurse Practitioner and Clinical Manager, Nephrology Associates of
Syracuse, PC, Syracuse, NY, and a member of ANNA’s Central New York
Chapter.
Sarah Chookie, LPN, is Nephrology Research Coordinator, Indiana Medical Associates LLC, Fort Wayne, IN.
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